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Concentration-dependent relaxation to LPI of methoxamine-induced tone in rat mesenteric resistance arteries. Responses were determined in the presence of functional endothelium. (A) Vessels were relaxed by LPI alone (n = 4), or in the presence of 10 μM indomethacin (n = 6). (B) Vessels were relaxed by LPI in the absence (n = 10) or presence (n = 4) of ODQ. Data are presented as means + SEM.
