Table 2.
Cetuximab (Arm A) | Cetuximab plus Sorafenib (Arm B) | ||
---|---|---|---|
Toxicity | Grade 3 | Grade 3 | Grade 4 |
Fatigue | 1 | 2 | 0 |
Infusion Reaction | 1 | 5 | 3 |
Maculopapular Rash | 1 | 2 | 0 |
Alkaline phosphatase | 0 | 2 | 0 |
Anemia | 0 | 1 | 0 |
Anorexia | 0 | 1 | 0 |
AST increased | 0 | 1 | 0 |
Diarrhea | 0 | 2 | 0 |
Dyspepsia | 0 | 1 | 0 |
Hypertension | 0 | 1 | 0 |
Hypokalemia | 0 | 1 | 0 |
Oral Mucositis | 0 | 2 | 0 |
Nausea | 0 | 1 | 0 |
Thromboembolic Event | 0 | 1 | 0 |
Total | 3 | 23 | 3 |
Grade 5 toxicites were not observed.