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. Author manuscript; available in PMC: 2015 Jun 8.
Published in final edited form as: J Alzheimers Dis. 2012;32(1):23–32. doi: 10.3233/JAD-2012-120430

Figure 2.

Figure 2

Proposed Mediation Model

Partial or complete mediation effects can be calculated from the attenuation of the direct path “a” after adjustment for the indirect paths “c” + “b”. When the mediator variable is sampled intermediately in time, between baseline and outcome measurements, the mediation effect is arguably causal.