Table 2. Effect of various intervals of gentamicin on renal function in minipigs.
day | 0 | 1 | 3 | 5 | 7 | 10 |
---|---|---|---|---|---|---|
BUN (mmol/L) | 3.8 ± 0.9 | 3.4 ± 0.5 | 4.4 ± 1.7 | 4.2 ± 0.6 | 5.1 ± 1.3 | 26.7 ± 8.2* |
Scr (μmol/L) | 80.9 ± 11.9 | 73.2 ± 15.8 | 68.2 ± 11.5 | 69.2 ± 6.8 | 101.3 ± 55.9 | 295.2 ± 65.3* |
BUN, blood urea nitrogen; Scr, serum creatinine. Values are presented as means ± SD (n = 6). *p < 0.05, vs. day 0.