Table 3. Effect of rapamycin on renal function in gentamicin-induced minipig.
CON | GEN | Rapa | |
---|---|---|---|
BUN (mmol/L) | 3.8 ± 0.9 | 26.7 ± 8.2 | 5.86 ± 2.93* |
Scr (μmol/L) | 80.9 ± 11.9 | 295.2 ± 65.3 | 135.8 ± 33.3* |
BUN, blood urea nitrogen; Scr, serum creatinine. CON, control group, GEN, gentamicin, Rapa, rapamycin. Values are presented as means ± SD (n = 6). *p < 0.05, vs. GEN.