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. 2015 Mar 18;24(13):3861–3870. doi: 10.1093/hmg/ddv091

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© The Author 2015. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — The association between groups defined by advanced age-related macular degeneration (AAMD)/CFI rare variant status and low serum FI level. Unadjusted analyses: estimated odds ratio of the association between AAMD/CFI rare variant status and low serum FI (≤29.3 µg/ml). Adjusted analyses: estimated odds ratio of the association between AAMD/CFI rare variant status and low serum FI (≤29.3 µg/ml) after adjusting for age at the time of blood sample (≤80, >80 yr), gender, body mass index (<25, ≥25) and smoking status (never, ever). All analyses used using exact binomial probabilities based on the exact option of PROC FREQ in SAS 9.3. OR: odds ratio; CI: confidence interval. ^aOR > 1 indicates that low serum FI increases risk, while OR < 1 indicates that low serum FI is protective.

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