Table 2.
Comparative analysis of the hemolysis parameters in sickle cell anemia patients (n = 50) and the control group (n = 20).
| Parameters | n | Patients Mean ± SEM |
n | Control Mean ± SEM |
p-value |
|---|---|---|---|---|---|
| Reticulocytes (%) | 50 | 13.85 ± 0.89 | 20 | 0.94 ± 0.09 | <0.0001 |
| LDH (U/L) | 50 | 636.20 ± 62.64 | 20 | 310.60 ± 8.39 | 0.0064 |
| Uric acid (mg/dL) | 50 | 5.46 ± 0.28 | 20 | 3.61 ± 0.17 | <0.0001 |
| Arginase I (ng/mL) | 50 | 71.87 ± 4.44 | 20 | 8.61 ± 0.36 | <0.0001 |
LDH: Lactate dehydrogenase.
Data are expressed as means ± standard error of the mean (SEM) and analyzed by the Mann–Whitney test and Unpaired t test; significant differences are defined as a p-value <0.05.