. Author manuscript; available in PMC: 2015 Jun 8.

Published in final edited form as: Semin Immunol. 2014 Feb 16;26(2):127–131. doi: 10.1016/j.smim.2014.01.010

TABLE 1.

COMPARISON OF NK CELL SUBPOPULATIONS

NK Cell Subpopulation	Transcription Factor Requirements	Cytokine Receptor Dependence	Functions	Location
cNK	NFIL3 (E4BP4)	IL-15R	Cytotoxicity, IFN-production	Spleen, blood, BM, liver
Thymic NK	GATA3	IL-15R, IL-7R	Cytotoxicity, IFN-production	Thymus, LN
uNK	?	IL-15R	Cytotoxicity, IFN-production	Uterus
trNK-liver	?	?	Cytotoxicity, IFN-production	Liver