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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1994 Aug 30;91(18):8307–8313. doi: 10.1073/pnas.91.18.8307

Increasing complexity of the dystrophin-associated protein complex.

J M Tinsley 1, D J Blake 1, R A Zuellig 1, K E Davies 1
PMCID: PMC44595  PMID: 8078878

Abstract

Duchenne muscular dystrophy is a severe X chromosome-linked, muscle-wasting disease caused by lack of the protein dystrophin. The exact function of dystrophin remains to be determined. However, analysis of its interaction with a large oligomeric protein complex at the sarcolemma and the identification of a structurally related protein, utrophin, is leading to the characterization of candidate genes for other neuromuscular disorders.

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Selected References

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