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. 2015 Jun 2;10:1027–1033. doi: 10.2147/COPD.S81748

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© 2015 Kurashima et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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The numbers of airways and vessels and the extent of emphysema.

Notes: The mean numbers of vessels (A) and airways (B) in 3 cm circles along right B1 to B10 airways were plotted to the mean percentage of low attenuation areas (%LAA). Segments (a) are under and (b) are above/on the linear regression lines. The subgroup of patients in (Aa) (n=36) who had less vessels along airways had larger annual decline of FEV₁ (−43.8 mL per year) compared to that of (Ab) (n=29) (−21.7 mL per year; P=0.015). The annual declines of FEV₁ in patients (a) and (b) in (B) were −40.6 mL per year (n=36) versus −26.4 mL per year (n=29), respectively (P=0.062).

Abbreviation: FEV₁, forced expiratory volume in 1 second.