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. 2015 Jun 2;10:3815–3827. doi: 10.2147/IJN.S82543

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© 2015 Chen et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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ALP activity and ALP staining assay.

Notes: (A) Relative ALP activity of hMSCs after 3, 7, and 14 days of co-culture with different samples (*P<0.05, compared to P0 at the same time; ^#P<0.05, compared to other scaffolds at the same time). (B) Images of positive ALP staining. The hMSCs were stained after being cultured with the four scaffolds respectively for 14 days. P2, P4, or P8 represents the PLGA scaffold coated by MBG precursor solution for 2, 4, or 8 times, respectively. P0 represents the unmodified PLGA scaffold.

Abbreviations: hMSCs, human mesenchymal stem cells; ALP, alkaline phosphatase; MBG, mesoporous bioactive glass; PLGA, poly(lactic-co-glycolic acid).