Table 2.

Means of sitting diastolic and systolic blood pressure at Weeks 4 and 8

Visit	Fimasartan/HCTZ (N=168)	Fimasartan (N=88)	Difference in change ± SD	95% confidence interval	P-value*
siDBP (mmHg)
Baseline	96.81±5.65	96.53±5.44
Week 4	89.93±9.14	93.16±8.87
Changea	−6.88±8.10	−3.38±7.33	−3.50±7.84	−5.53, −1.47	0.0008
Week 8	88.14±9.65	91.51±9.84
Changeb	−8.67±9.39	−5.02±8.27	−3.65±9.02	−5.99, −1.31	0.0023
siSBP (mmHg)
Baseline	150.77±12.65	149.40±11.87
Week 4	140.27±15.55	143.65±14.76
Changea	−10.50±13.76	−5.75±12.18	−4.75±13.24	−8.18, −1.32	0.0069
Week 8	137.32±15.90	142.56±16.22
Changeb	−13.45±15.15	−6.84±13.57	−6.61±14.63	−10.40, −2.82	0.0007

Notes: Data are expressed as mean ± SD.

^aChange from baseline at Week 4;

^bchange from baseline at Week 8;

^*P-value by two-sample t-test.

Abbreviations: HCTZ, hydrochlorothiazide; SD, standard deviation; siDBP, sitting diastolic blood pressure; siSBP, sitting systolic blood pressure.