Assessment of renal disease in combined groups of WKY rats (n=20) immunized with pCol(24–38) peptide, c- 3-Gly peptide and scrambled peptide. Results shown represent the mean ± SD in each group. (A) albuminuria at different time points after immunization (*p<0.001; pCol(24–38) versus scrambled, and c- 3-Gly versus scrambled), (B) glomerular abnormalities at week 6 or week 8 after immunization (*p<0.005; pCol(24–38) versus scrambled, **p<0.05; c- 3-Gly versus scrambled), and (C) deposits of IgG on the GBM at week 6 or week 8 after immunization (*p<0.001; pCol(24–38) versus scrambled).