Table 2.
All grade adverse events.
| Adverse event | Grade | ||||
|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | |
| Leukopenia | 11 | 10 | 12 | 3 | 0 |
| Thrombocytopenia | 30 | 4 | 0 | 1 | 0 |
| Neutropenia | 20 | 6 | 6 | 1 | 2 |
| Anemia | 3 | 6 | 22 | 4 | 0 |
| Nausea/vomiting | 15 | 11 | 9 | 0 | 0 |
| Other GI | 13 | 10 | 10 | 2 | 0 |
| GU | 34 | 1 | 0 | 0 | 0 |
| Neurotoxicity | 15 | 11 | 8 | 1 | 0 |
| Pain | 20 | 9 | 4 | 2 | 0 |
| Pulmonary | 30 | 1 | 2 | 2 | 0 |
| Cardiovascular | 34 | 0 | 1 | 0 | 0 |
| Constitutional (Fatigue) | 8 | 7 | 15 | 5 | 0 |
| Metabolic | 24 | 5 | 2 | 4 | 0 |
| Dermatologic | 30 | 1 | 3 | 1 | 0 |
| Alopecia | 17 | 3 | 15 | - | - |
| Musculoskeletal | 32 | 2 | 1 | 0 | 0 |
| Auditory | 31 | 0 | 1 | 0 | 0 |
| Infection | 27 | 0 | 4 | 4 | 0 |
| SGOT | 34 | 1 | 0 | 0 | 0 |
| Alkaline phosphatase | 34 | 1 | 0 | 0 | 0 |
| Lymphatics | 31 | 2 | 2 | 0 | 0 |
No treatment related deaths have been reported.