Figure 3.

Cytobiology change after treating cells with miR-218 mimics. (A) Transwell assay was performed as described in Materials and methods. The representative images of invasive cells at the bottom of the membrane stained with crystal violet were visualized as shown (left). The quantifications of cell migration were presented as percentage migrated cell numbers and the integrated intensity of migrated cells (right). * indicates significant difference compared with control group (P < 0.05). (B) EDU assay was performed as described. The integrated density was presented with mean ± SE. * indicates significant difference compared with control group P < 0.05.