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. 2015 Mar 5;19(6):1273–1283. doi: 10.1111/jcmm.12485

Table 2.

Summary of immunochemical staining of the different tissue types in negative control group, positive control group and fibrous tissue with Collagen I and Collagen II

Tissue type Coll I Coll II
Bone Cartilage Fibrous tissue Bone Cartilage Fibrous tissue
Negative control + + −/+ +++ +
Positive control + nm +++ nm
Periosteum flap + ++ −/+ +++ ++

The original cartilage as well as the neo-cartilage show characteristic positive results for Coll II, but not for Coll I, which is slightly expressed in bone and strong in fibrous tissue (nm: non-measurable, as there is no fibrous tissue located in the positive control sections). Please see also the pictures (Figure5).