Figure 4.
Effect of celecoxib on the expression of P-gp, BCRP and iNOS in mitochondria of MDR1-positive P1(0.5) cells. Mitochondria of P1(0.5) cells were purified by using the fraction methodology based on iodixanol separation as described in the Materials and methods section. HSP-60 were used as a protein-loading control. One experiment representative of the three performed is shown.