Table 2.

Predictors of early-onset PG

Variables	Est.	SE	P-value	Odds Ratio (95% C.I.)
Age	−0.103	0.015	<0.001	0.90 (0.88, 0.93)
Male gender	1.496	0.420	<0.001	4.46 (1.96, 10.16)
Any substance use disorder	0.946	0.458	0.039	2.58 (1.05, 6.32)
ADHD	1.636	0.596	0.006	5.13 (1.60, 16.52)
Study group*
Family study probands	−1.100	0.468	0.019	0.33 (0.13, 0.83)
Family study relatives	−0.465	0.628	0.458	0.63 (0.18, 2.15)

Results based on multiple logistic regression analyses with stepwise variable selection.

^*Subjects from the longitudinal study used as reference group.

ADHD=attention deficit/hyperactivity disorder