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. Author manuscript; available in PMC: 2016 Jul 15.
Published in final edited form as: Bioorg Med Chem Lett. 2015 May 11;25(14):2837–2843. doi: 10.1016/j.bmcl.2015.04.104

Figure 8. Red blood cell lysis in response to treatment with Compounds 1–6.

Figure 8

Freshly isolated human RBCs were treated with specified amounts of cationic lipids, and hemoglobin (Hb) release was measured after one hour of treatment at 37°C. Results are represented as means, and error bars show the standard deviation from four replicates at each condition. Monosubstituted products show very little to no RBC hemolysis at all concentrations tested. Disubstituted products show hemolysis at concentrations greater than 50 μM.