Table 4.
Comparison of the fit of competing twin models of the nature of the MD-T2DM relationship: Age 40 – 55
| Model description | Log-likelihood | AIC | Degrees of freedom difference vs. Bivariate ACE |
P value |
|---|---|---|---|---|
| Full Bivariate ACE (Non-causal: MD-T2DM due to shared genetic and/or environmental factors) | 4626.04 | −10135.96 | -- | -- |
| Bidirectional causation (MD ↔ T2DM) | 4623.16 | −10140.85 | 1 | 0.99 |
| Unidirectional causation (MD→ T2DM) | 4626.49 | −10139.51 | 2 | 0.80 |
| Unidirectional causation (T2DM→ MD) | 4630.00 | −10136.00 | 2 | 0.14 |
| No correlation between MD and T2DM | 4636.43 | −10131.57 | 3 | 0.024 |
P-value from −2Log-likelihood test of relative model fit. Limited to twins aged 40 – 55.