Fig. 2.
Cell types based on synaptic responses to stimulation of inferior colliculus (IC) axons. Current-clamp responses to single synaptic stimuli are shown. The top traces in A–D show cells in standard artificial cerebrospinal fluid (aCSF). The bottom traces in A–D show the same cells when ionotropic glutamate receptors were blocked with dl-2-amino-5-phosphonopentanoic acid (APV) + 6,7-dinitroquinoxaline-2,3-dione (DNQX). A: a P29 cell with a purely inhibitory response type (IN/0 cell). B: a P16 mixed type cell where the inhibitory postsynaptic potential (IPSP) preceded the excitatory postsynaptic potential (EPSP) (IN/EX cell). C: a P17 mixed type cell where the EPSP preceded the IPSP (EX/IN cell). D: a P9 cell with a dominant excitatory component (EXDOM cell). E–G: proportions of cell types at P27 (E), P16 (F), and P8 (G).