Table 3.
Development of IPSP and IPSC amplitudes
| P8 | P16 | P27 | |
|---|---|---|---|
| Latency | |||
| Combined IPSP latency, ms | 3.0 ± 0.4b (n = 11) | 3.2 ± 0.3e (n = 17) | 1.9 ± 0.1 (n = 16) |
| GABAA IPSP latency, ms | 2.9 ± 0.7 (n = 4) | 3.3 ± 0.6 (n = 6) | 2.0 ± 0.2 (n = 6) |
| Latency of GABAA IPSC, ms | 3.2 ± 0.2 (n = 4) | 3.0 ± 0.3 (n = 4) | 2.2 ± 0.4 (n = 4) |
| Rise time | |||
| Combined IPSP rise time, ms | 11.6 ± 1.2a,d (n = 11) | 7.3 ± 0.7 (n = 17) | 5.8 ± 0.5 (n = 16) |
| GABAA IPSP rise time, ms | 14.5 ± 2.8c (n = 4) | 9.2 ± 1.8 (n = 6) | 7.1 ± 0.6 (n = 6) |
| GABAA IPSC rise time, ms | 1.7 ± 0.3 (n = 4) | 3.4 ± 0.2 (n = 4) | 2.9 ± 0.5 (n = 3) |
| Decay time | |||
| Decay time of GABAA IPSP from all cells, ms | 138.0 ± 25.7a,b (n = 4) | 67.6 ± 2 (n = 6) | 61.1 ± 6.4 (n = 6) |
| Decay time of GABAA IPSC, ms | 8.9 ± 1.1 (n = 4) | 12 ± 1.4 (n = 4) | 10.8 ± 1.7 (n = 4) |
Values are shown as means ± SE; n, number of cells.
a
P < 0.01, P8 vs. P16;
b
P < 0.05,
c
P < 0.01, and
d
P < 0.001, P8 vs. P27;
e
P < 0.01, P16 vs. P27.