Table 3.
Cortex | Hippocampus | Amygdala | ||||
---|---|---|---|---|---|---|
WT | IL-4 KO | WT | IL-4 KO | WT | IL-4 KO | |
NE | 1.58 ± 0.14 | 1.59 ± 0.11 | 2.36 ± 0.08 | 2.45 ± 0.14 | 2.15 ± 0.06 | 2.09 ± 0.08 |
NME | 0.17 ± 0.01 | 0.16 ± 0.03 | 0.25 ± 0.03 | 0.26 ± 0.05 | 0.17 ± 0.02 | 0.19 ± 0.04 |
DA | 6.17 ± 0.71 | 6.75 ± 0.58 | 0.06 ± 0.01 | 0.07 ± 0.01 | 0.87 ± 0.06 | 0.77 ± 0.08 |
DOPAC | 0.46 ± 0.04 | 0.47 ± 0.03 | 0.09 ± 0.01 | 0.13 ± 0.01 | 0.22 ± 0.02 | 0.21 ± 0.02 |
HVA | 0.80 ± 0.08 | 0.84 ± 0.07 | 0.18 ± 0.02 | 0.20 ± 0.02 | 0.30 ± 0.01 | 0.27 ± 0.03 |
5-HT | 1.34 ± 0.05 | 1.39 ± 0.07 | 2.74 ± 0.12 | 2.96 ± 0.19 | 4.25 ± 0.13 | 4.25 ± 0.15 |
5-HIAA | 0.51 ± 0.03 | 0.49 ± 0.03 | 1.89 ± 0.07 | 2.03 ± 0.11 | 1.37 ± 0.03 | 1.39 ± 0.08 |
Results are expressed as means ± SEM; no significant results seen with respect to WT vs. IL-4 KO at p<0.05; n=6