Fig 7. Retinal function analysis in S. aureus virulence factors challenged eyes.
Eyes of C57BL/6 mice (4–6 per group) were inoculated intravitreally with S. aureus (5000CFU), HKSA (5x105 CFU), LTA (0.1μg), PGN (0.1μg), SPA (0.1μg), TSST1 (0.1μg), α-toxin (0.1μg), and PBS (2μl). ERG was performed after overnight dark adaptation. Electroretinogram responses to a 6-dB flash were recorded and the percentage amplitude of a- and b-wave retained in infected eyes was compared to that of uninjected mice control and presented as mean ± SD. ERG amplitudes Statistical analysis was performed using one-way ANOVA with Dunnett’s multi-comparison test. *p <0.05, **p <0.005, ***p <0.001 (n = 6 mice were used per treatment). UN,uninjected.