Table 2. Experimental groups of titer-matched scAAV-injected and mock-injected eyes.
Group | AAV Serotype | n |
---|---|---|
1 | AAV2 | 5 |
2 | AAV2(Y444F) | 5 |
3 | AAV2(triple) | 5 |
4 | AAV2(septuple) | 5 |
5 | AAV8(Y733F) | 5 |
6 | vehicle control | 5 |
7 | no injection | 5 |
A sample size of 5 eyes per group was analyzed by immunohistochemistry for GFP-expression. The experimental protocol was performed in C57BL/6 mice and Sprague Dawley rats.