. 2015 Jun 8;10(6):e0128759. doi: 10.1371/journal.pone.0128759

Table 3. Localization of the GFP signal in the anterior section of eyes injected with similar titers of scAAVs.

	Vector	C57BL/6 Mice (Injection Vol 1 μL)	Sprague Dawley Rats (Injection Vol 2 μL)
Group 1	scAAV2 WT~2x10¹²	cornea—NPE + chamber angle + iris -	cornea—NPE—chamber angle + iris +
Group 2	scAAV2(Y444F) ~9x10¹¹	cornea + NPE ++ chamber angle ++ iris+	cornea—NPE ++ chamber angle ++ iris +
Group 3	scAAV2(triple) ~3x10¹²	cornea ++^*NPE ++ chamber angle ++ iris +	cornea ++^*NPE ++ chamber angle ++ iris +
Group 4	scAAV(septuple) ~2x10¹²	cornea—NPE-/+ chamber angle—iris -	cornea—NPE—chamber angle-/+ iris-/+
Group 5	scAAV8(Y733F) ~2x10¹²	cornea -^**NPE—chamber angle—iris-/+	cornea -^**NPE—chamber angle—iris -

The transduction efficiency (grading:-,-/+, +, ++) is based on the intensity and distribution of the GFP signal in tissues of the anterior section. Unless otherwise noted (see asterisks) the term cornea represents GFP-expression in the corneal endothelium.

* One out of five showed GFP-positivity in the corneal stroma in addition to the corneal endothelium.

** One out of five showed GFP-positivity in the corneal stroma.