Table 3. Quantitative results, including the average beta values (i.e., high-memory-load activation) and the average z scores (i.e., ECN connectivity), within the ICA-derived ECN regions in APOE-ε4 carriers and non-carriers.
Average beta values | Average z scores | ||||
---|---|---|---|---|---|
Region | Side | APOE-ε4 carriers | APOE-ε4 non-carriers | APOE-ε4 carriers | APOE-ε4 non-carriers |
Medial Frontal Gyrus | L | -0.37 ± 0.55 | 0.02 ± 0.66 | 0.23 ± 0.13 | 0.18 ± 0.19 |
Middle Frontal Gyrus | L | -0.41 ± 0.38 | 0.06 ± 0.43* | 0.2 ± 0.09 | 0.17 ± 0.11 |
Inferior Frontal Gyrus | L | -0.74 ± 0.69 | 0.16 ± 0.74* | 0.43 ± 0.21 | 0.36 ± 0.34 |
Precentral Gyrus | R | -0.38 ± 0.42 | -0.02 ± 0.65 | 0.35 ± 0.16 | 0.29 ± 0.16 |
Superior Temporal Gyrus | R | -0.28 ± 0.67 | -0.12 ± 0.88 | 0.33 ± 0.15 | 0.25 ± 0.2 |
Middle Temporal Gyrus | L | -0.5 ± 0.51 | 0.08 ± 0.42* | 0.09 ± 0.17 | 0.22 ± 0.21 |
R | -0.16 ± 0.6 | -0.07 ± 0.6 | 0.12 ± 0.3 | 0.24 ± 0.24 | |
Angular Gyrus | L | -0.48 ± 0.83 | 0.04 ± 0.57 | 0.14 ± 0.14 | 0.18 ± 0.19 |
Inferior Parietal Lobule | L | -0.56 ± 1.28 | 0.1 ± 0.72 | 0.18 ± 0.17 | 0.21 ± 0.2 |
Cingulate Gyrus | L | -0.2 ± 0.74 | 0.33 ± 0.66 | -0.01 ± 0.11 | 0 ± 0.15 |
Anterior insula | L | -0.17 ± 0.17 | 0.13 ± 0.45 | 0.18 ± 0.13 | 0.03 ± 0.13* |
R | -0.26 ± 0.37 | 0.06 ± 0.47 | 0.28 ± 0.21 | 0.05 ± 0.14* |
*: p < 0.05, compared with APOE-ε4 carriers.
ECN = executive control network; ICA = independent component analysis; L = left hemisphere; R = right hemisphere.