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. 2015 Jun 9;9:214. doi: 10.3389/fncel.2015.00214

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Copyright © 2015 Bing, Wu, Chu and Qiu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Blocking N-methyl-D-aspartate (NMDA) receptors during 1 Hz stimulation abolished the LTD of GABAergic transmission at PCs. (A) Upper, representative cell-attached recording traces showing air-puff stimulation (10 ms, 60 psi)-evoked responses in a PC before (pre) and after (post) delivery of 1 Hz (240 pulses) stimulation delivered in the presence of NMDA receptor antagonist, D-APV (50 μM). (B) Summary of data showing normalized amplitude of P1 before (pre) and after (post) delivery of 1 Hz (240 pulses) stimulation. (C) Pooled data showing the normalized pause of SS firing before (pre) and after (post) delivery of 1 Hz (240 pulses) stimulation.