Table 3.
Comparison of the heart to mediastinum ratio in DLB and AD
| Authors (y) | NC | DLB | AD | Cutoff | Sensitivity | Specificity |
|---|---|---|---|---|---|---|
| Yoshita et al. (2001) [32] | NI | E: 1.31 ± 0.17 | E: 2.26 ± 0.29 | NI | NI | NI |
| D: 1.18 ± 0.10 | D: 2.22 ± 0.30 | |||||
| Watanabe et al. (2001) [106] | E: 2.40 ± 0.10 | E: 1.40 ± 0.20 | E: 2.30 ± 0.20 | NI | NI | NI |
| D: 2.40 ± 0.20 | D: 1.20 ± 0.20 | D: 2.40 ± 0.20 | ||||
| Oide et al. (2003) [103] | NI | E: 1.49 ± 0.25 | E: 2.18 ± 0.23 | NI | NI | NI |
| Hanyu et al. (2006) [104] | E: 2.50 ± 0.35 | D: 1.31 ± 0.34 | D: 2.35 ± 0.47 | D: 1.73 | D: 95% | D: 87% |
| D: 2.37 ± 0.32 | ||||||
| Hanyu et al. (2006) [108] | E: 2.56 ± 0.37 | E: 1.61 ± 0.32 | E: 2.55 ± 0.39 | NI | NI | NI |
| D: 2.53 ± 0.38 | D: 1.33 ± 0.16 | D: 2.41 ± 0.41 | ||||
| Yoshita et al. (2006) [113] | E: 1.33 ± 0.17 | D: 1.68 | D: 100% | D: 100% | ||
| E: 2.07 ± 0.21 | D: 1.22 ± 0.12 (DLB/P+) | E: 2.16 ± 0.26 | ||||
| D: 2.18 ± 0.26 | E: 1.48 ± 0.39 | D: 2.19 ± 0.28 | ||||
| D: 1.26 ± 0.14 (DLB/P-) | ||||||
| Wada-Isoe et al. (2007) [109] | E: 2.23 ± 0.31 | E: 1.54 ± 0.25 | E: 2.28 ± 0.40 | E: 1.81 | E: 85% | E: 100% |
| D: 2.16 ± 0.41 | D: 1.31 ± 0.22 | D: 2.22 ± 0.34 | D: 1.82 | D: 100% | D: 90.6% | |
| Estorch et al. (2008) [110] | NI | E: 1.30 ± 0.25 | E: 1.79 ± 0.20 | D: 1.36 | D: 94% | D: 96% |
| D: 1.16 ± 0.13 | D: 1.73 ± 0.26 | |||||
| Slaets et al. (2014) [17] | NI | NI | NI | D: 1.68 | D: 100% | D: 75% |
| Yoshita et al. (2015) [137] | NI | E: 1.97 ± 0.62 | E & D: 2.10 | E & D: 68.9% | E & D: 89.1% | |
| D: 1.79 ± 0.73 (probable DLB) | E: 2.72 ± 0.54 | |||||
| E: 2.32 ± 0.71 | D: 2.77 ± 0.70 (probable AD) | |||||
| D: 2.32 ± 0.88 (possible DLB) |
DLB: dementia with Lewy bodies, AD: Alzheimer’s disease, E: early heart to mediastinum ratio, D: delayed heart to mediastinum ratio, NC: normal control, DLB/P+: dementia with Lewy bodies with parkinsonism, DLB/P-: dementia with Lewy bodies without parkinsonism.