Table 3.
Parent-reported clinical symptoms* in patients with eosinophilic esophagitis and associations with PEESS® v2.0 Score
| Clinical Symptom | N | Frequency (%) |
PEESS® v2.0 Score | |||||
|---|---|---|---|---|---|---|---|---|
| Total | Dysphagia domain |
GERD domain |
Nausea/Vomiting domain |
Pain domain |
||||
| Swallowing | Food Impaction | 46 | 8.7 | -- | -- | -- | -- | -- |
| Choking/gagging | 46 | 21.7 | -- | -- | -- | -- | -- | |
| Clinical Dysphagia | 46 | 28.3 | -- | 25.0 (0.0012) | -- | -- | -- | |
| Difficulty Swallowing | 46 | 21.7 | 22.9 (0.0006) | 29.4 (0.0017) | -- | -- | 25.0 (0.0005) | |
| Chest Pain | 46 | 19.6 | -- | -- | -- | -- | -- | |
| Generalized Gastrointestinal | Heartburn | 46 | 28.3 | 21.2 (0.0002) | 27.6 (0.0023) | 12.5 (0.0002) | 37.5 (0.0026) | 25.0 (0.0003) |
| Reflux | 45 | 33.3 | -- | -- | 14.6 (0.0001) | -- | -- | |
| Poor Appetite | 46 | 43.5 | 12.5 (0.0014) | -- | -- | -- | -- | |
| Food Aversions | 46 | 26.1 | 17 (0.0011) | -- | -- | -- | -- | |
| Weight Loss | 46 | 15.2 | -- | -- | -- | -- | -- | |
| Abdominal Pain | 46 | 47.8 | 15.6 (0.0004) | -- | -- | -- | 21.8 (0.0002) | |
| Early Satiety | 46 | 50.0 | -- | -- | -- | -- | -- | |
| Poor Weight Gain | 45 | 20.0 | -- | -- | -- | -- | -- | |
| Nausea | 46 | 43.5 | 13.1 (0.0027) | -- | -- | 34.4 (<0.0001) | 21.8 (0.0004) | |
| Emesis | 46 | 23.9 | -- | -- | -- | 43.8 (< 0.0001) | -- | |
| Diarrhea | 46 | 37.0 | -- | -- | -- | -- | -- | |
| Constipation | 46 | 17.4 | -- | -- | -- | -- | -- | |
| Bloody Stools** | 46 | 4.3 | -- | -- | -- | -- | -- | |
*
Symptoms are separated by swallowing and generalized gastrointestinal.
Those with significant differences (p < 0.003 are reported as median difference between those with and without the condition (p value).
**
The condition was too infrequent in the study cohort for comparative analyses.
-- non-significant
GERD, gastroesophageal reflux disease