Figure 1.
(A) T1-Gd MRI at baseline (left) and 80 months post-RT (right) of a 14 yo female patient with diffuse astrocytoma who underwent stereotactic biopsy and definitive radiation followed by alkylating chemotherapy. (B) Representative voxel within the enhancing lesion (left) and MRS spectrum demonstrating elevated Cho peak, decreased NAA peak and small lactate peak (right). (C) 11C-MET PET demonstrating increased uptake in lesion. (D) Image of biopsy specimen of lesion demonstrating viable tumor cells consistent with recurrent disease. Adapted from Nakajima et al.31 Copyright permission pending.
