Table 4.
Correlations of twenty-six Drugs with hypertension
| ID | Drug ID | Drug Name | Correlation (CTD, N, or Unknown) | ID | Drug ID | Drug Name | Correlation (CTD, N, or Unknown) |
|---|---|---|---|---|---|---|---|
| 1 | DB00315 | Zolmitriptan[60] | N | 14 | DB01622 | Thioproperazine | Unknown |
| 2 | DB00476 | Duloxetine[61] | N | 15 | DB06701 | Dexmethylphenidate | Unknown |
| 3 | DB04896 | Milnacipran[56] | N | 16 | DB08810 | Cinitapride | Unknown |
| 4 | DB06204 | Tapentadol[62] | N | 17 | DB01363 | Ephedra [55] | N |
| 5 | DB06684 | Vilazodone[63] | N | 18 | DB00472 | Fluoxetine | CTD |
| 6 | DB06700 | Desvenlafaxine [57] | N | 19 | DB00176 | Fluvoxamine | CTD |
| 7 | DB08918 | Levomilnacipran [64] | N | 20 | DB00543 | Amoxapine | CTD |
| 8 | DB00805 | Minaprine | Unknown | 21 | DB01104 | Sertraline | CTD |
| 9 | DB00952 | Naratriptan | Unknown | 22 | DB06148 | Mianserin | CTD |
| 10 | DB00998 | Frovatriptan | Unknown | 23 | DB01577 | Methamphetamine | CTD |
| 11 | DB01614 | Acepromazine | Unknown | 24 | DB01151 | Desipramine | CTD |
| 12 | DB01616 | Alverine | Unknown | 25 | DB00852 | Pseudoephedrine | CTD |
| 13 | DB01621 | Pipotiazine | Unknown | 26 | DB00514 | Dextromethorphan | CTD |
Drug ID represents the unique DrugBank accession number of a drug. Drug Name represents the corresponding name of a Drug ID. There are three types of correlation: (a) CTD represents the drug-hypertension correlation that can be found in the CTD database; (b) N represents the drug-hypertension correlation that may be negative, supported by literature; (c) Unknown means that there is no evidence suggesting the drug-hypertension relation as yet.