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. 2015 May 26;16(Suppl 5):S2. doi: 10.1186/1471-2164-16-S5-S2

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Copyright © 2015 Hamed et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Regulatory interactions of the 17 key driver genes identified from miRNA-mRNA interactions. Large nodes represent key driver genes and small nodes represent miRNAs, which regulate or are regulated by these driver genes. Square nodes are the identified driver genes that are targeted by drugs. The network was visualized using the Igraph package in R.