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. 2015 Jun 10;16:61. doi: 10.1186/s12863-015-0223-y

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© Ye et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The haplotype structure of HFE. SNPs within 20 Kb of HFE were used in this analysis. Data were retrieved from Hapmap 3. Each node represents one haplotype and the size of each node is proportional to the frequency of the haplotype among all haplotypes observed. Each node is also a pie chart and each sector represent the contribution of each population. The line between two nodes represents the evolutionary connection between the two haplotypes and the mutations to convert the two haplotypes are indicated on the line. The red arrow points to the Asia-prevalent haplotype, H19. The green node represents the haplotype (H1) observed in Chimpanzees