Table 1.
Variable | C/C (N = 10) | T/T (N = 11) |
---|---|---|
Age (y) | 22.8 ± 4.0(18-31) | 21.2 ± 1.8 (18-24) |
Hemoglobin (g/dL) | 12.8 ± 0.8 (11.3-14.1) | 13.3 ± 1.2 (11.1-14.7) |
Serum ferritin (ug/L) | 36.3 ± 28.3 (7-89.7) | 36.7 ± 33.6 (7.4-124) |
Serum transferrin receptor (mg/L) | 3.2 ± 1.2 (1.7-5.0) | 4.76 ± 1.81* (2.7-8.9) |
Serum hepcidin (ng/mL) | 17.8 ± 14.2 (1.4-38.5) | 16.0 ± 16.7 (0.7-51.5) |
NOTE.—Data are expressed as the mean ± SD with the range in parentheses. Iron status indicators were measured in blood obtained 2-weeks post-dosing. Similar patterns were observed using data from the screening day and the dosing day. * indicates p = 0.021 in one-tailed Wilcoxon rank sum test between the two genotypes