Table 1.
Variables | Baseline | 8 week post-transplant | Reference |
---|---|---|---|
Clinical | |||
Body mass index, kg/m2 | 25.6 | 29.1 | - |
Resting SBP, mm Hg | 82 | 124 | - |
Resting DBP, mm Hg | 50 | 82 | - |
Echocardiography | |||
LV ejection fraction, % | 62.3 | 63.3 | ≥50 |
E/mean e' | 8.0 | 9.9 | ≤10 |
Vascular | |||
Aortic PWV (m/s) | 5.9 | 6.4 | 4.5–9.6 |
AIx75 (%) | 21 | 28 | 19–24 |
Biochemical | |||
Creatinine, μmol/l | 446 | 139 | 50–90 |
eGFR, ml/min/1.73 m3 | - | 39 | >60 |
Hemoglobin, g/dl | 13.2 | 9.1 | 12–15 |
Albumin, g/l | 44 | 44 | 35–50 |
Cortisol, nmol/l | 433 | 356 | 150–720 |
Aldosterone, pmol/l | |||
Pre-exercise | 515 | 372 | 28–445 |
Post-exercise | 1342 | - | 28–445 |
Renin, mU/l | |||
Pre-exercise | <9.0 | 9.0 | 9.8–23.8 |
Post-exercise | <9.0 | - | 9.8–23.8 |
Cardiopulmonary exercise test | |||
FEV1/FVC, % | 78 | 77 | 75–80 |
VO2peak, % predicted | 73 | 73 | - |
VO2AT, % of VO2peak predicted | 41 | 48 | - |
Oxygen pulse, ml O2/min | 9.4 | 9.3 | |
Maximal work load, Watt | 88 | 99 | - |
Endurance time, min | 10.4 | 11.3 | - |
RER at peak exercise | 1.4 | 1.3 | - |
HR at rest, beat/min | 82 | 73 | - |
HR at peak exercise, beat/min | 141 | 142 | - |
LV left ventricular, E/mean e' ratio of early transmitral flow velocity to annular mitral velocity (averaged of septal and lateral), PWV pulse wave velocity, AIx 75 augmentation index corrected to heart rate, FEV 1 /FVC, ratio of forced expiratory volume in 1 s to full vital capacity, VO 2 peak oxygen consumption at peak exercise, VO 2 AT oxygen consumption at the point of anaerobic threshold, RER respiratory exchange ratio of CO2 production to O2 consumption, HR heart rate