Cox 2014.

Trial name or title	Ready‐to‐use supplementary food supplements improve endothelial function, haemoglobin and growth in Tanzanian children with sickle cell anaemia: the vascular function intervention study (V‐FIT), a random order crossover trial.
Methods	Randomised cross‐over trial.
Participants	Tanzanian children (n = 119) with sickle cell anaemia aged 8 ‐ 11.9 years.
Interventions	Daily ready‐to‐use supplementary food providing 500 kcal, 1 RDA of vitamins and minerals and 1 mg folate (Nutriset, France), plus weekly anti‐malarial prophylactic chloroquine syrup (150/225 mg base) (Wallace Manufacturing Chemicals, UK), or a vascular ready‐to‐use supplementary food fortified with arginine and citrulline (average 0.2 g/kg/d and 0.1 g/kg/d) plus daily chloroquine syrup (3 mg base/kg/d).
Outcomes	Height, weight and body composition by impedance, endothelium‐dependent and ‐independent vasodilatation.
Starting date	November 2012.
Contact information	Sharon Cox (sharon.cox@lshtm.ac.uk).
Notes	Study author contacted for availability of study findings.

RDA: recommended daily allowance