Table 3.
The correlation between the postoperative systemic inflammatory response and the clinicopathological factors
Postoperative NLR | Postoperative GPS | |||||
---|---|---|---|---|---|---|
<3 | ≥3 | p value | 0 | 1,2 | p value | |
Age (years) | ||||||
<70 | 120 | 19 | 102 | 28 | ||
≥70 | 63 | 15 | 0.331 | 57 | 18 | 0.729 |
Gender | ||||||
Male | 97 | 24 | 84 | 27 | ||
Female | 86 | 10 | 0.063 | 75 | 19 | 0.506 |
Location | ||||||
Colon | 93 | 19 | 86 | 22 | ||
Rectum | 90 | 15 | 0.709 | 73 | 24 | 0.504 |
Tumor depth | ||||||
T1-3 | 133 | 22 | 112 | 33 | ||
T4 | 49 | 12 | 0.406 | 47 | 13 | 1.000 |
Histological type | ||||||
Well, moderately | 170 | 31 | 147 | 43 | ||
Poorly, mucinous | 12 | 3 | 0.711 | 12 | 2 | 0.739 |
Lymphatic involvement | ||||||
Negative | 39 | 5 | 35 | 3 | ||
Positive | 124 | 27 | 0.363 | 112 | 37 | 0.026 |
Venous involvement | ||||||
Negative | 123 | 24 | 109 | 35 | ||
Positive | 46 | 9 | 1.000 | 41 | 8 | 0.321 |
Number of lymph node metastases | ||||||
0 | 75 | 8 | 60 | 7 | ||
1–3 | 71 | 19 | 64 | 30 | ||
≥4 | 37 | 7 | 0.116 | 35 | 9 | 0.005 |
Preoperative CEA (>5 ng/ml) | ||||||
Negative | 129 | 25 | 116 | 29 | ||
Positive | 38 | 6 | 0.816 | 35 | 8 | 1.000 |
Preoperative CA19-9 (>37 U/ml) | ||||||
Negative | 158 | 28 | 145 | 33 | ||
Positive | 5 | 2 | 0.298 | 3 | 4 | 0.031 |
Adjuvant chemotherapy | ||||||
No | 40 | 4 | 35 | 8 | ||
Yes | 143 | 30 | 0.246 | 124 | 28 | 0.545 |
Length of operation (min) | ||||||
Median (range) | 199 (79–430) | 230 (84–687) | 0.010 | 203 (79–687) | 206 (110–372) | 0.681 |
Blood loss (ml) | ||||||
Median (range) | 80 (5–1785) | 220 (10–2700) | <0.001 | 80 (5–2700) | 90 (10–1880) | 0.495 |
Postoperative infectious complication | ||||||
No | 137 | 25 | 121 | 34 | ||
Yes | 46 | 9 | 0.833 | 38 | 12 | 0.846 |
Preoperative NLR | ||||||
<2.5 | 70 | 12 | ||||
≥2.5 | 45 | 8 | 1.000 | |||
Preoperative GPS | ||||||
0 | 131 | 21 | ||||
1,2 | 24 | 20 | <0.001 |
NLR neutrophil-to-lymphocyte ratio, GPS Glasgow prognostic score, CEA carcinoembryonic antigen, CA19-9 carbohydrate antigen 19-9