Table 3.
Summary of different comparative meta-analysis results
| Polymorphism | Genetic model | Participants | OR (95% CI) | Z | P value | I 2 % | P het | Effect model | Begg’s test p > │z│ | Egger’s test p > │t│ |
|---|---|---|---|---|---|---|---|---|---|---|
| rs187084 | TT vs. TC + CC | 1331 | 0.93 (0.75, 1.15) | 0.68 | 0.49 | 0.0 | 0.91 | F | 0.29 | 0.30 |
| CC vs. TC + TT | 1331 | 1.12 (0.77, 1.63) | 0.60 | 0.55 | 0.0 | 0.53 | F | 0.30 | 0.47 | |
| TT vs. CC | 784 | 0.85 (0.58, 1.27) | 0.79 | 0.43 | 0.0 | 0.6 | F | 0.30 | 0.47 | |
| TT vs. TC | 1208 | 0.95 (0.75, 1.19) | 0.50 | 0.63 | 0.0 | 0.91 | F | 0.30 | 0.17 | |
| T vs. C | 2660 | 0.93 (0.79, 1.10) | 0.80 | 0.43 | 0.0 | 0.78 | F | 1.00 | 0.57 | |
| rs5743836 | TT vs. TC + CC | 1241 | 1.18 (0.90, 1.54) | 1.18 | 0.24 | 0.0 | 0.82 | F | 0.30 | 0.36 |
| CC vs. TC + TT | 1241 | 0.99 (0.68, 1.45) | 0.06 | 0.95 | 0.0 | 0.58 | F | 1.00 | _ | |
| TT vs. CC | 831 | 1.12 (0.72, 1.73) | 0.5 | 0.62 | 0.0 | 0.63 | F | 1.00 | _ | |
| TT vs. TC | 1110 | 1.19 (0.90, 1.57) | 1.18 | 0.24 | 0.0 | 0.82 | F | 1.00 | 0.48 | |
| T vs. C | 2482 | 1.09 (0.90, 1.33) | 0.89 | 0.37 | 0.0 | 0.72 | F | 0.30 | 0.15 | |
| rs352139 | AA vs. AG + GG | 2404 | 0.88 (0.65, 1.19) | 0.83 | 0.40 | 62.1 | 0.049 | R | 0.09 | 0.00 |
| GG vs. AG + AA | 2404 | 0.90 (0.60, 1.35) | 0.51 | 0.61 | 61.9 | 0.049 | R | 0.73 | 0.59 | |
| AA vs. AG | 2081 | 0.84 (0.63, 1.12) | 2.9 | 0.004 | 55.4 | 0.081 | R | 0.31 | 0.07 | |
| AA vs. GG | 1311 | 1.02 (0.65, 1.61) | 0.1 | 0.92 | 62.0 | 0.048 | R | 0.73 | 0.24 | |
| A vs. G | 4808 | 0.98 (0.77, 1.25) | 0.17 | 0.87 | 72.5 | 0.012 | R | 0.09 | 0.10 |
Phet = P value for heterogeneity; OR = odds ratio; CI = confidence interval; F = fixed-effect model; R = random-effect model.