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. 2015 Jun 9;5:11100. doi: 10.1038/srep11100

Figure 2. In vitro dynamic effects of edaravone and diethyl maleate (DEM) treatments of human umbilical cord mesenchymal stem cells (hUCMSCs) on cell apoptosis after lipopolysaccharide (LPS)/H2O2 intoxication (n = 4).

Figure 2

(a) Apoptotic ratio, (b) caspase-3/7 activity, (c) cellular Bcl-2 mRNA expression and (d) cellular Bax1 mRNA expression of each group of hUCMSCs after different durations of LPS/H2O2 challenge. LPS, LPS/H2O2 challenge; Eda10, 10 μM edaravone; Eda20, 20 μM edaravone. “**” means P < 0.01 against control group; “***” means P < 0.001 against control group; “#” means P < 0.05 against LPS/H2O2 group; “##” means P < 0.01 against LPS/H2O2 group; “###” means P < 0.001 against LPS/H2O2 group.