TABLE 1.
Effect of UL20p plus gK on the cell surface expression of glycoproteins
| Transfected protein | Cell surface expressiona of:
|
% Inhibition | |
|---|---|---|---|
| Glycoproteinb | Glycoprotein + gK + UL20pc | ||
| wt gB | 13.27 ± 2.01d | 10.51 ± 1.70 | 21 |
| gBΔ867 | 23.23 ± 3.70 | 7.74 ± 1.75 | 24 |
| gD | 26.1 ± 3.51 | 17.04 ± 2.65 | 35 |
| gH | 15.15 ± 3.54 | 9.35 ± 2.13 | 38 |
| gL | 25.05 ± 2.01 | 19.50 ± 2.16 | 22 |
| EGFR2Δ | 24.68 ± 2.05 | 22.71 ± 2.12 | 8 |
a
Expressed as the percentage of unfixed cells reacting with the appropriate glycoprotein Ab (mean ± SE) as determined by FACS analysis. Values shown are from three or more determinations.
b
COS cells were transfected with the indicated glycoprotein plasmid.
c
COS cells were transfected with the indicated glycoprotein plasmid, UL20p, and gK.