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. 2004 Aug;78(15):7916–7924. doi: 10.1128/JVI.78.15.7916-7924.2004

FIG. 2.

FIG. 2.

EV71 induces apoptosis of Caco-2 and SK-N-SH cells. (A) Caco-2 or SK-N-SH cells were infected with the parental (Tainan/4643/98) or mouse-adapted (MP4) EV71 strain at an MOI of 1. The expressions of both the proform and the cleavage form of caspase 9 in whole-cell lysates were determined by Western blotting. (B) Apoptosis of EV71-infected cells was determined by flow cytometry after staining with Annexin V. Values are the means ± SEM of results of three independent experiments. *, P value of <0.05 compared with the results for the same cell type infected with 4643.