Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mouse-adapted EV71 induces death in mice after oral inoculation. Seven-day-old ICR mice were orally inoculated with the parental (Tainan/4643/98) or mouse-adapted (MP4) EV71 strain at 1 × 104 to 5 × 106 PFU/mouse (A) or 5 × 106 PFU/mouse (B), both at 200 μl, with or without i.p. administration of mouse anti-EV71 serum (50 μl). Survival was then monitored daily after infection. Control mice were given cell lysate instead of virus suspension. Each group contained six to eight mice.
