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. Author manuscript; available in PMC: 2016 Jun 15.
Published in final edited form as: Methods. 2015 Mar 14;81:41–49. doi: 10.1016/j.ymeth.2015.03.006

Figure 1. ABPP-LC-MRM and pY-LC-MRM Kinome Coverage.

Figure 1

Kinases are color coded for whether LC-MRM is able to detect ABPP peptides (gray), pY peptides (light brown), or both (dark brown). The inset (upper right) shows the total numbers of proteins included unique each assay and the overlap between ABPP and pY datasets. In total, 264 protein kinases are monitored with 412 ABPP peptides using 1,628 total transitions. For phosphotyrosine quantification, 126 proteins (including 60 kinases) are monitored with 377 pY peptides using 1,488 total transitions.