Table 3.
Intention-to-treat analysis at post-treatment and at 60-week post-treatment follow-up.
| Effect estimates for CBT-E vs IPT post-treatment | Effect estimate for CBT-E vs IPT 60-week follow-up | |||||
|---|---|---|---|---|---|---|
| Difference | (95% CI) | p value | Difference | (95% CI) | p value | |
| Body mass index (kg/m2) | 0.14 | (−0.42–0.71) | 0.621 | −0.59 | (−1.50–0.32) | 0.204 |
| Eating disorder psychopathology (EDE) | ||||||
| Global score | −0.81 | (−1.23–−0.40) | <0.001 | −0.28 | (−0.74–0.18) | 0.230 |
| Dietary restraint | −1.39 | (−1.89–−0.89) | <0.001 | −0.42 | (−0.98–0.14) | 0.142 |
| Eating concern | −0.69 | (−1.14–−0.23) | 0.003 | −0.23 | (−0.68–0.21) | 0.304 |
| Shape concern | −0.54 | (−0.99–−0.08) | 0.021 | −0.29 | (−0.85–0.26) | 0.303 |
| Weight concern | −0.66 | (−1.21–−0.11) | 0.019 | −0.28 | (−0.82–0.26) | 0.308 |
| Other features | ||||||
| Secondary Impairment (CIA) | −6.22 | (−10.10–−2.33) | 0.002 | −1.33 | (−5.72–3.05) | 0.551 |
| Depressive features (BDI) | −1.76 | (−5.86–2.34) | 0.399 | 1.12 | (−3.40–5.63) | 0.628 |
| Odds ratio | (95% CI) | p value | Odds ratio | (95% CI) | p value | |
| EDE severity score < 1 SD above the community mean (<1.74) | 8.75 | (2.59–29.54) | <0.001 | 4.20 | (1.17–15.14) | 0.028 |
| Eating disorder behaviour (EDE) | ||||||
| Objective bulimic episodes ≥1 | 0.24 | (0.08–0.75) | 0.014 | 0.80 | (0.24–2.66) | 0.714 |
| Self-induced vomiting ≥1 | 0.22 | (0.04–1.09) | 0.064 | 0.84 | (0.15–4.79) | 0.843 |
| Laxative-taking ≥1 | 0.03 | (0.00–0.54) | 0.018 | 0.11 | (0.00–2.82) | 0.183 |
| Absence of all of the above | 6.68 | (1.89–23.59) | 0.003 | 1.04 | (0.29–3.67) | 0.954 |
EDE – Eating Disorder Examination (Fairburn et al., 2008); CIA – Clinical Impairment Assessment (Bohn & Fairburn, 2008; Bohn et al., 2008); BDI – Beck Depression Inventory (Beck et al., 1961).
Estimated treatment differences are from longitudinal mixed effects linear or logistic regression models which included data from all participants who were randomised (IPT: 65; CBT: 65), account for missing data and repeated measures on individuals over time and adjust for baseline values of the outcome in question.