Table 1.
Basic characteristics of lean and diet-induced obesity (DIO) C57BL/6J mice exposed to chronic intermittent hypoxia (CIH) or control for 4 weeks
Characteristics |
Lean mice |
DIO mice |
|||
---|---|---|---|---|---|
Exposure | Control | CIH | Control | CIH | |
N | 8 | 8 | 10 | 8 | |
Body weight (g) | |||||
Day 0 | 23.5 ± 0.3 | 24.2 ± 1.0 | 33.0 ± 1.5* | 33.5 ± 1.6* | |
Day 28 | 25.7 ± 0.4 | 23.0 ± 0.6** | 34.9 ± 1.3* | 34.9 ± 1.7* | |
Mean food intake (g/day) | 3.22 ± 0.26 | 2.97 ± 0.49 | 3.34 ± 0.39 | 2.83 ± 0.38 | |
Liver weight | (g) | 0.92 ± 0.04 | 0.86 ± 0.02 | 1.31 ± 0.10* | 1.10 ± 0.06* |
Percentage of body weight | 4.08 ± 0.11 | 4.18 ± 0.06 | 4.25 ± 0.22 | 3.64 ± 0.18† | |
Epididymal fat | (g) | 0.48 ± 0.02 | 0.35 ± 0.03** | 1.56 ± 0.24* | 1.65 ± 0.22* |
Percentage of body weight | 1.94 ± 0.09 | 1.53 ± 0.12*** | 4.45 ± 0.55* | 4.83 ± 0.60* |
CIH, chronic intermittent hypoxia; DIO, diet-induced obesity.
P < 0.01 vs. lean mice.
P < 0.01 vs. control lean mice.
P < 0.05 vs. control lean mice.
P = 0.05 vs. control DIO mice.