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. 2015 Jun 3;10:3779–3790. doi: 10.2147/IJN.S83279

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© 2015 Li et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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NanoATV/r and FA-nanoATV/r biodistribution in kidney, spleen, and liver as quantified by UPLC-MS/MS.

Notes: ATV concentration in tissues is shown for nanoATV/r in (A) LPS and (B) nanoATV/r treated mice. Data are presented as mean ± SEM, *P<0.05 considered significant using Student’s t-test. Panel A and B are days 7 and 14 after nanoformulation treatment, respectively.

Abbreviations: nanoATV/r, nanoformulated ritonavir (RTV)-boosted atazanavir (ATV); FA, folic acid; UPLC-MS/MS, ultraperformance liquid chromatography tandem mass spectrometry; LPS, lipopolysaccharide.