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. 2015 Jun 3;10:3779–3790. doi: 10.2147/IJN.S83279

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© 2015 Li et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Immunofluorescence staining of FAPM biodistribution in LPS-treated mouse spleen (top) or nanoATV/r treated mouse spleen (bottom).

Notes: (A) Phase contrast; (B) DAPI; (C) Iba-1; (D) folate receptor 2; (E) magnetite (arrow indicates individual magnetite); and (F) merged picture. 200×, white arrows indicate colocalized stains.

Abbreviations: FAPM, ALN-PEG-FA-coated magnetite; LPS, lipopolysaccharide; nanoATV/r, nanoformulated ritonavir (RTV)-boosted atazanavir (ATV); DAPI, 4′,6-diamidino-2-phenylindole; Iba-1, ionized calcium-binding adaptor molecule 1; ALN, alendronate; PEG, polyethylene glycol; FA, folic acid.