Table 2.

MICs for ceftolozane/tazobactam against select bacterial causes of cIAI

Organisms	MIC range (mg/L)
P. aeruginosa with efflux pumps	0.5
P. aeruginosa with decreased OprD expression	0.5
E. coli CTX-M-15	0.25–2
E. coli SHV-5	0.25–2
K. pneumoniae CTX-M-15	0.25–64
K. pneumoniae KPC	>16
Bacteroides fragilis	<0.12–>16; MIC50 =1

Abbreviations: MICs, minimum inhibitory concentrations; cIAI, complicated intra-abdominal infections.