Table 2.

Laboratory characteristics of patients with NASH

	NASH				P-value
	Stage 0–1	Stage 2	Stage 3	Stage 4
ALT (IU/L)	50.0±31.7	74.7±62.6	65.1±37.3	47±57.4	0.0302
AST (IU/L)	31.6±11.9	51.3±36.7	50±24	42.8±22.8	0.0002
γ-GTP (IU/L)	70.5±64	53.4±37.3	57.1±34.6	73.1±53.1	0.6556
Cholinesterase (U/L)	361±98	338±105	330±90	298±93	0.124
Total bilirubin (mg/dL)	0.9±0.3	0.8±0.2	0.9±0.4	0.9±0.4	0.8791
Platelets (104/μL)	22.1±5.9	21.2±6.8	20.6±7.1	14.3±4.5	0.0004
Albumin (g/dL)	4.6±0.2	4.4±0.3	4.3±0.3	4.1±0.5	<0.0001
Total cholesterol (mg/dL)	193±38.3	201±28.2	195±24.8	186±55.2	0.6063
Triglyceride (mg/dL)	155±84.9	142.2±58.7	147.5±77.8	103.6±26.4	0.199
HDL-C (mg/dL)	48.5±11.2	43.5±9.2	47.7±18.1	46.9±13	0.3756
LDL-C (mg/dL)	114.9±34.4	129.4±24.1	118.5±27.3	118.7±52.7	0.2545
Serum iron (μg/dL)	121±32	110±38	115±37	132±56	0.3812
Ferritin (ng/mL)	143±95	144±128	168±154	202±323	0.9584
Hyaluronic acid (ng/mL)	36.8±25.1	55±58	76±108	168±142	0.0002
P-III-P (U/mL)	0.56±0.12	0.6±0.2	0.75±0.5	0.7±0.18	0.0146
Type IV collagen 7S (ng/mL)	3.6±0.6	4.0±0.9	4.7±1.3	5.6±1.5	<0.0001
hs-CRP (mg/dL)	152±213	197±213	222±224	145±102	0.3092
HOMA-IR	2.7±2	3.5±2.5	3.6±1.6	3.4±1.6	0.0034
Leptin (ng/mL)	8.3±5.5	12.5±11.4	17.1±12.2	12.3±9.6	0.0018
Adiponectin (μg/mL)	7.0±3.9	7.3±3.8	6.1±2.6	7.4±3.8	0.7889

Note: Data are presented as mean ± standard deviation.

Abbreviations: NASH, nonalcoholic steatohepatitis; ALT, alanine aminotransferase; AST, aspartate aminotransferase; γ-GTP, γ-glutamyl transpeptidase; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; P-III-P, type III procollagen-N-peptide; hs-CRP, high-sensitivity C-reactive protein; HOMA-IR, homeostasis model assessment of insulin resistance.